LymphedemaV1, Main, Exploration, bibRecord, 006684

Cutaneous epithelioid angiosarcoma: a neoplasm with potential pitfalls in diagnosis

Identifieur interne : 006684 ( Main/Exploration ); précédent : 006683; suivant : 006685

Cutaneous epithelioid angiosarcoma: a neoplasm with potential pitfalls in diagnosis

Auteurs : Narciss Mobini [États-Unis]

Source :

Journal of Cutaneous Pathology [ 0303-6987 ] ; 2009-03.

RBID : ISTEX:C12DFA3C7D86B594FC2830B11ADF632D3C3E7D48

Descripteurs français

KwdFr :
- Adulte d'âge moyen, Diagnostic différentiel, Femelle, Humains, Hémangiosarcome (anatomopathologie), Mâle, Mélanome (anatomopathologie), Sujet âgé de 80 ans ou plus, Tumeurs cutanées (anatomopathologie).
MESH :
- anatomopathologie : Hémangiosarcome, Mélanome, Tumeurs cutanées.
- Adulte d'âge moyen, Diagnostic différentiel, Femelle, Humains, Mâle, Sujet âgé de 80 ans ou plus.

English descriptors

KwdEn :
- Aged, 80 and over, Diagnosis, Differential, Female, Hemangiosarcoma (pathology), Humans, Male, Melanoma (pathology), Middle Aged, Skin Neoplasms (pathology).
MESH :
- pathology : Hemangiosarcoma, Melanoma, Skin Neoplasms.
- Aged, 80 and over, Diagnosis, Differential, Female, Humans, Male, Middle Aged.

Abstract

Angiosarcoma (AS) is a rare neoplasm. Cutaneous AS is the most common form of AS. The epithelioid variant of the disease, however, is a rare entity. This subset can histologically mimic non‐vascular neoplasms and impose serious challenges in reaching the correct diagnosis. We present five patients with cutaneous epithelioid angiosarcoma (EAS); in none, the clinical diagnosis included a vascular lesion. Three patients had history of breast conservation surgery with/without radiation therapy. Other patients had no previous radiation, and there was no lymphedema in any of the cases. The histopathological examination of the biopsy specimens by hematoxylin and eosin method was not suggestive of a malignant vascular neoplasm initially and the differential diagnoses included carcinoma, malignant melanoma and atypical lymphoid infiltrate. Only after performing immunohistochemical studies that included vascular markers, a definitive diagnosis was possible. Some cases showed unusual histopathological features. Cutaneous EAS is a rare variant of cutaneous AS that can mimic a variety of more common, non‐vascular neoplasms, creating a major pitfall in the diagnosis. A careful and thorough histopathological examination and a high index of suspicion, along with appropriate immunohistochemical evaluation, can help reach a correct diagnosis and provide optimal patient care.

Url:

https://api.istex.fr/document/C12DFA3C7D86B594FC2830B11ADF632D3C3E7D48/fulltext/pdf

DOI: 10.1111/j.1600-0560.2008.01052.x

Affiliations:

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<front><div type="abstract" xml:lang="en">Angiosarcoma (AS) is a rare neoplasm. Cutaneous AS is the most common form of AS. The epithelioid variant of the disease, however, is a rare entity. This subset can histologically mimic non‐vascular neoplasms and impose serious challenges in reaching the correct diagnosis. We present five patients with cutaneous epithelioid angiosarcoma (EAS); in none, the clinical diagnosis included a vascular lesion. Three patients had history of breast conservation surgery with/without radiation therapy. Other patients had no previous radiation, and there was no lymphedema in any of the cases. The histopathological examination of the biopsy specimens by hematoxylin and eosin method was not suggestive of a malignant vascular neoplasm initially and the differential diagnoses included carcinoma, malignant melanoma and atypical lymphoid infiltrate. Only after performing immunohistochemical studies that included vascular markers, a definitive diagnosis was possible. Some cases showed unusual histopathological features. Cutaneous EAS is a rare variant of cutaneous AS that can mimic a variety of more common, non‐vascular neoplasms, creating a major pitfall in the diagnosis. A careful and thorough histopathological examination and a high index of suspicion, along with appropriate immunohistochemical evaluation, can help reach a correct diagnosis and provide optimal patient care.</div>
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Cutaneous epithelioid angiosarcoma: a neoplasm with potential pitfalls in diagnosis

Cutaneous epithelioid angiosarcoma: a neoplasm with potential pitfalls in diagnosis

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

	Serveur d'exploration sur le lymphœdème
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